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Specifically, while chronic, low-dose SFN may be ideal for prevention, its use as an adjunct to chemotherapy in established cancers requires careful scheduling to avoid potential protection of tumor cells

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doi: 10.1016/S0140-6736(19)30417-9 4 MurphyLBHelmickCGSchwartzTARennerJBTudorGKochGGet al

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Some preliminary evidence indicates that significant weight loss achieved through any mechanism, including pharmacotherapy, may reduce levothyroxine requirements in some patients, necessitating monitoring of thyroid function and potential dose adjustment