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Correspondingly, GLP-1Rs are widely, yet region-specifically, distributed throughout the rat brain, including the olfactory bulb, cerebral cortex, hippocampus, lateral septum, amygdala, nucleus accumbens, multiple hypothalamic nuclei (such as the paraventricular nucleus, supraoptic nucleus, arcuate nucleus, and dorsomedial nucleus), ventral tegmental area, substantia nigra, raphe nuclei, parabrachial nucleus, locus coeruleus, nucleus tractus solitarius, area postrema, and dorsal motor nucleus of the vagus nerve

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