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Then, radiolabeled 125 I-GLP-1 (40 pM, PerkinElmer) and increasing concentrations of unlabeled peptide were added and competitively reacted with the cells in binding buffer (PBS supplemented with 10% (w/v) BSA, pH 7.4) at RT for 3 h

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Patient samples and CAR T cell therapy De-identified clinical samples were collected from a subset of adult patients with relapsed/refractory B-ALL who received investigational CD19-specific CAR T cells in a phase 1/2 clinical trial (NCT02146924) at our institution 29

Nadia Khan, a clinician scientist at the University of British Columbia in Vancouver and the principal investigator on the study, told us she and her colleagues felt they couldnt accept a retraction unless they had more information on what the specific issues were, and whether the issues constituted enough of a departure to warrant a retraction. Khan and two other authors also practice at Revolution Medical Clinic, a Vancouver clinic that provides obesity and metabolic disease treatment