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(AUI), on behalf of North America

In summary, the findings of impaired IGF-1 synthesis, together with modest elevation of GH-levels due to decreased renal clearance, and increased IGF plasma binding capacity, provides evidence of a multilevel, homeostatic failure in the GH-IGF-1 system in CKD, which has paved the way for studies proving the stimulatory growth effects of GH in short children with CKD [163]

Frontiers in Cellular Neuroscience, 2015

Here, the blood vessels connected to the brain become clogged, which obstructs the flow of blood that reaches the brain

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