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SKU: 36222169104

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Five Core Biological Actions The 2015 and 2018 Pickart and Margolina reviews catalog the biological actions of GHK-Cu across in vitro, animal, and human studies 1 2

434,435,436 In addition, fluoxetin-induced activation of astrocytic 5-HT 2B receptors induces transactivation of epidermal growth factor receptors, which, in turn, recruit MAPK/ERK or PI3K/AKT signalling cascades to regulate expression of several genes (such as Ca 2+ -dependent phospholipase A2, cPLA2, subtype 2 of adenosine deaminases acting on RNAs, ADAR2, or subtype 2 of kainate receptors, GluK2) related to mood disorders