GDC-0623 Size:Solid 10 mg Molecular Weight: 439

Molecular Weight: 439

5-3(6)1-2-4(7)8/h2-9

The hematopoietic cancer c-Kit+

InChiKey: WRUWGLUCNBMGPS-UHFFFAOYSA-N

68-40)50(59)51(60)54-23-15-14-18-41(54)52(61)67-45(35(4)28-39-20-22-43(66-25-24-55)46(29-39)64-9)31-42(56)34(3)27-37(6)48(58)49(65-10)47(57)36(5)26-32/h11-13

GDC-0623 Size:Solid 10 mg Molecular Weight: 439GDC 0623, also known as G 868, is an orally active, selective MEK inhibitor with potential antineoplastic activity. MEK inhibitor GDC 0623 specifically inhibits mitogen activated protein kinase kinase (MEK or MAP ERK kinase), resulting in inhibition of growth factor mediated cell signaling and tumor cell proliferation. MEK is a key component of the RAS RAF MEK ERK signaling pathway that regulates cell growth; constitutive activation of this pathway