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Necrostatin-1 faxine Hydrochloride a potent and selective inhibitor

SKU: 59570538340

4.4
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Necrostatin-1 faxine Hydrochloride a potent and selective inhibitorNecrostatin 1 is a potent and selective inhibitor of necroptosis, a mechanism of programmed cell death separate from apoptosis. Necrostatin 1 functions as an allosteric inhibitor of the death domain receptor associated adaptor kinase RIP (RIP1) in the necroptosis pathway. While affecting this distinct cell death pathway, Necrostatin 1 does not present any perturbation of the Fas TNFR triggered canonical apoptosis cascade. Necrostatin 1 inhibits RIP1

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Description

a potent and selective inhibitor of polo-like kinase 1

ClH/c1-9(2)4(7)8-3(5)6

Formula: C21H17NO3S2

InChi: InChI=1S/C18H15NO8S2

CAS Number: 101831-37-2

Necrostatin-1 faxine Hydrochloride a potent and selective inhibitorNecrostatin 1 is a potent and selective inhibitor of necroptosis, a mechanism of programmed cell death separate from apoptosis. Necrostatin 1 functions as an allosteric inhibitor of the death domain receptor associated adaptor kinase RIP (RIP1) in the necroptosis pathway. While affecting this distinct cell death pathway, Necrostatin 1 does not present any perturbation of the Fas TNFR triggered canonical apoptosis cascade. Necrostatin 1 inhibits RIP1

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