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doi: 10.1038/s41598-020-76896-4 154 MoumneOHampeMEMontoya-WilliamsDCarsonTLNeuJFrancoisMet al

System x C inhibitors specifically exploit this vulnerability to preferentially kill cancer cells with stabilized mutant-p53 protein

D-amino acid metabolism (involved metabolites: D-alanyl-D-alanine, diaminopimelic acid, D-alanine), peptidoglycan biosynthesis (involved metabolites: D-alanyl-D-alanine

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In conclusion, the structure of the GLP-2GLP-2RG s complex delineates detailed interactions between GLP-2 and GLP-2R that account for the peptide binding specificity, and provides new insights into the structural reorganization of class B GPCRs upon activation