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Regarding BMI, our results showed that GLP-1 agonists had a progressive impact on BMI reduction over time, with statistically significant effects emerging at 6 months and persisting up to 24 months, at 3 months, the mean difference (MD) was 0.36 (95% CI: 1.22, 0.50) with 0.0% heterogeneity ( I 2 ) and a p -value of 0.4102

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MNT also spoke with Verna Porter, MD, a board certified neurologist and director of the Dementia, Alzheimers Disease and Neurocognitive Disorders at Pacific Neuroscience Institute at Providence Saint Johns Health Center in Santa Monica, CA, about this study, who said her first reaction is one of cautious optimism

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Regulation of mitochondrial NADP+-dependent isocitrate dehydrogenase activity by glutathionylation