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Transplantation Proceedings, 42 (2), 5635

Understanding these deep cellular mechanisms is crucial when exploring how a doctor diagnoses Long COVID and why one-size-fits-all treatments often fail

Proton pump inhibitors: Examples include omeprazole, esomeprazole and lansoprazole

Further mechanistic studies showed that NNMTi increases intracellular NAD levels and activates the SIRT1 pathway by inhibiting NNMT, thereby suppressing the transcription of adipogenic genes and preventing the maturation of preadipocytes.This research provides a new perspective for understanding the molecular mechanism of adipocyte differentiation, confirms the key role of NNMTi in regulating adipogenesis, and lays a foundation for subsequent obesity intervention studies