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Human trials showed that in people with high-risk features, treatment with minocycline reduced in 6 months the risk of conversion to MS, decreased lesion volume, and showed the absence of new enhancing lesions, but this effect did not last beyond 24 months of study (Preiningerova et al., 2022)

A triple agonist is a single molecule designed to bind to and activate three distinct cellular receptors simultaneously

Methods In a 71-week, double-blind, randomized, placebo-controlled trial conducted at 22 sites in four countries, we enrolled persons without diabetes who had a body-mass index (BMI

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Hypoglycaemia This is a rare and serious side effect

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