fda glp-1 compounding enforcement september 2025 Safe use of compounded GLP products Non-Traditional Channels: The Compounded GLP-1

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The results showed that both DA3-CH and Liraglutide could reduce MPTP-induced neuroinflammatory responses, inhibit the proliferation of microglia and astrocytes, and DA3-CH had significantly better effects than Liraglutide, as shown in Figure 3 ( Figure 3 In another study comparing the neuroprotective effects of two other novel GLP-1/GIP dual receptor agonists (DA-JC4, DA-CH5) with the GLP-1 single receptor agonist liraglutide and the first-generation GLP-1/GIP dual receptor agonist DA-JC1 in MPTP-induced PD mice, the results concluded that the new dual receptor agonists have clear neuroprotective effects (Figure 4 illustrates some of the findings

Morrison H, Young K, Qureshi M, Rowe RK, Lifshitz J (2017) Quantitative microglia analyses reveal diverse morphologic responses in the rat cortex after diffuse brain injury

clinical corroboration is needed